Brazil's COVID-19 vaccine volunteer dies, authorities say trial to continue

Brazil's COVID-19 vaccine volunteer dies, authorities say trial to continue

Both the AstraZeneca and J&J vaccines are based on adenoviruses, cold germs that researchers have used in experimental therapies for decades, and the two paused trials have raised questions about the approach.

The Federal University of Sao Paulo, which is helping coordinate phase 3 clinical trials in Brazil, separately said that the volunteer was Brazilian but did not say where the person lived. And a robust way to interrupt viral transmission.

The World Health Organization (WHO) has identified 42 candidate vaccines in clinical trials, ten of which are in the most advanced "phase 3" stage.

AstraZeneca said medical confidentiality meant it could not give details on any individual volunteer, but that independent review had "not led to any concerns about continuation of the ongoing study".

At a recent Health, Education, Labor, and Pensions Committee hearing, FDA commissioner Dr. Stephen Hahn and CDC director Dr. Robert Redfield committed that their respective agencies would conduct oversight measures, including allowing their independent advisory committees to meet, review data and issue public findings as part of the expedited COVID-19 vaccine review process.

Yet Doshi argues that vaccine makers "have done little to dispel the notion" that severe COVID-19 was what was being assessed.

In an email statement to CNN, Oxford University said: "All significant medical incidents, whether participants are in the control group or the Covid-19 vaccine group, are independently reviewed".

And few if any current trials are created to find out whether there is a benefit among the elderly, a key atrisk constituency.

That opinion, however, was shared by only 29% of Black respondents - far below the 70% of Asian Americans, 62% of white people and 54% of Latinos who said they would definitely or probably get vaccinated.

Once a vaccine is widely available and in use, scientists hope people can stop wearing face masks to stop the spread of the virus, Ogbuagu says. On an investor call, AstraZeneca CEO Pascal Soriot specified that one patient was diagnosed with multiple sclerosis unrelated to the vaccine, and the second experienced spinal inflammation known as transverse myelitis, according to STAT News.

However, this depends on the number of COVID-19 cases in the phase 2/3 trial, which must reach a certain number in order to compare the effectiveness of the vaccine compared to placebo.

The COVID-19 disease is spreading more quickly than during its initial outbreak in the spring, French government scientific advisor Arnaud Fontanet said today.

Three COVID-19 trials are on hold as cases surge, with an average of over 60,000 new cases per day in the USA over the last week.

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