Moderna Announces its COVID Vaccine is 94.5 Percent Effective

Moderna Announces its COVID Vaccine is 94.5 Percent Effective

News from USA drug company Moderna Inc. that its potential COVID-19 vaccine candidate has also been more than 90 per cent effective in clinical trials sent stock markets soaring on Monday, boosting hopes that the global economy may soon fully convalesce and things could get back to normal.

U.S. biotech firm Moderna on Monday announced its experimental vaccine against Covid-19 was nearly 95 percent effective, marking a second major breakthrough in the quest to end the pandemic. Russian Federation licensed its "Sputnik-V" COVID-19 vaccine for domestic use in August before it released data from large-scale trials.

For the second time in as many weeks, a pharmaceutical giant is out with successful news about a COVID-19 vaccine.

Citing early results, Massachusetts-based Moderna said its vaccine candidate could be as much as 94.5 per cent effective.

Moderna has a $1.525 billion contract to provide the United States with 100 million doses of the vaccine through Operation Warp Speed, the government's fast-track program for Covid-19 vaccines, therapeutics, and diagnostics.

Its first analysis was based on 95 cases of COVID-19, 90 of which received a placebo with 5 receiving the vaccine.

Europe's health regulator said on Monday it had launched a real-time "rolling review" of Moderna's vaccine, as it has done for vaccines from Pfizer and AstraZeneca. All 11 cases occurred in the placebo group and none in the mRNA-1273 vaccinated group. Both vaccines require two doses to be administered. "Since early January, we have chased this virus with the intent to protect as many people around the world as possible", Stéphane Bancel, chief executive officer of Moderna, said in a statement.

The company believes that the vaccine can be stored at standard refrigeration temperatures of between 2C and 8C for up to 30 days and that is can be stored at -20C for six months.

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The data from Moderna's trial involving 30,000 volunteers also showed the vaccine prevented cases of severe Covid-19, a question that still remains with the Pfizer vaccine.

"Once again, I congratulate the brilliant women and men who produced this breakthrough and have brought us one step closer to beating this virus".

The vaccine can then be stored safely in a normal refrigerator for at least five days after being thawed out, possibly even longer, but again, we don't know yet. Moderna has received almost $1 billion in research and development funding from the USA government and has a $1.5 billion deal for 100 million doses.

The vaccine is already being mass-produced and thousands of doses will be ready to ship following authorization.

The DAK President said that this creates a challenge for the proper distribution and storage of the vaccine as most hospitals do not have storage facilities for a vaccine at such an ultra-low temperature. This included 20 people who were not white - including 12 of whom were from Hispanic or Latino/a backgrounds, four African Americans, three Asian Americans and one who was multiracial.

The agreement with Moderna has passed the exploratory talks stage with the aim of sealing a deal to get around 160m doses for member states. With a pandemic raging, companies are more likely to quickly find an answer about whether the vaccines work or not.

The main side effects were fatigue, muscle aches and injection-site pain after the vaccine's second dose, at rates that Hoge characterized as higher than with flu shots but on par with others such as shingles vaccine. Most of these complaints were generally short-lived, the company said. "The big cities that have access to deep freezers clustered around academic research centers, there you would probably use the Pfizer vaccine, whereas in the rural areas, or away from the medical centers, you would presumably want to utilize your warmer-temperature vaccine", Kinch said. Moderna was up 7.5% in the morning, while companies that have benefited from the stay-at-home economy were down, including Zoom, Peloton and Netflix. Brussels also said it was in talks with Moderna about securing doses.

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